Spider-Man 2 offers a ton of extra content for players to get into. After you have completed the main mission, you still have plenty to do around New York City to ensure that everyone in the city is safe and sound.
One way that you can ensure this is by completing the many side quests in the game. Along with side quests, you can unlock and complete District Activities. These are certain activities around NYC that need doing.
How To Unlock Cultural Museum Missions
Once you reach the quest “Funky,” which is the 14th quest in the main questline, you can unlock the Cultural Museum missions throughout New York City. In this quest, Miles will find criminals who have broken into the museum and have stolen some of the most important instruments in the place. You must play as Miles for these.
How To Unlock EMF Experiments
If you want to unlock the Emily-May Foundation Experiments (EMF Experiments), you will need to complete the 8th main mission, “Healing the World.” After this, you will explore the foundation and open up these many activities around the city. You must play as Peter during these quests.
How To Unlock FNSM Requests
You can unlock FNSM once you have finished the main quest “One Thing at a Time.” This is the second quest in the main questline. After you are able to start roaming around New York on your own, you can slide on the trackpad in order to open up the FNSM app and track requests. You can play as either Spider-Man.
How To Unlock Hunter Bases
Once you complete the quest “Bad Guys on the Block,” which is the 9th quest in the main questline, you can unlock these. During this quest, you will uncover the cloaking devices that the Hunters are using. You can then find their bases around the city. You can play as either Spider-Man.
How To Unlock Hunter Blinds
Just like with Hunter Bases, you will need to complete the 9th quest in the main questline, “Bad Guys on the Block.” Once that is finished, you will find the Hunter Blinds scattered around New York City. You can play as either Spider-Man.
How To Unlock Marko’s Memories
To unlock Marko’s Memories, you will need to fight Sandman. During this fight, you will find the first crystal that contains a memory of Marko’s. Once you have destroyed it, you will find them all over the city. You can play as either Spider-Man during this.
How To Unlock Mysteriums
In order to unlock these, you must finish the main quest “Master Illusionist.” This quest is the 11th in the main questline and is where Miles will go to Coney Island and enter into the first Mysterium. You must play as Miles during these.
How To Unlock Photo-Ops
You will unlock Photo-Ops during the quest “Show Me New York.” This is the 3rd quest in the main questline. You will need to travel around taking photos of the true New York. During this mission, you can play as either Spider-Man.
How To Unlock Prowler Stashes
During the quest “Not On My Watch,” Miles’ uncle, Aaron Davis (AKA Prowler), will ask Miles if he will travel around the city looking for his Prowler Stashes. This is the 6th mission in the main questline. You must be Miles during this.
How To Unlock Spider-Bots
Spider-Bots will unlock after the main mission quest “Science Buddy.” This quest is the 13th quest in the main questline. During this, you will need to track down all the Spider-Bots that are roaming the city. Either Spider-Man is able to do this.
How To Unlock Symbiote Nests
After the main quest “It’s All Connected,” you will be able to unlock the Symbiote Nests. This is one of the last main missions in the game and is number 31 out of 34 main quests. Either Spider-Man is able to complete these.
How To Unlock The Flame Missions
These quests will unlock after the quest “Amends” is completed. This is the 7th quest in the main questline. Once you have completed that, Yuri will have you help her take out the cult around New York. You need to be Peter for this.
How To Unlock Unidentified Targets
The Unidentified Targets are unlocked after the quest “Stay Positive.” This is the 19th quest in the main questline of the game. This requires you to follow one of the drones around until you find the target. You can be either Spider-Man in this quest.